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Klaus Mathwig University of Groningen, Groningen Research Institute of Pharmacy, Pharmaceutical Analysis,Groningen, The Netherlands

Event Date: 
Thursday, August 23, 2018 - 11:00am to 12:00pm
Title: Nanofluidic Electrochemical and Electrochemiluminescent Sensing Abstract: The miniaturization of lab-on-a-chip analytical systems allows new approaches that are not possible with bulk techniques. The confinement to a microfluidic channel enables handling and analysis on a single cell level. Similarly, by reducing the molecular reaction space to a nanochannel, small molecules can by sensed in novel ways. The effect of nanoscale confinement can both lead to improvement in practical sensing devices for point-of-care applications as well as for fundamental studies of, e.g., single molecules. I will to introduce nanofluidic devices, which utilize the unique properties of nanochannels, and focus on two applications: Electrochemical correlation spectroscopy or stochastic amperometry: This technique allows extraction of molecular properties, namely diffusivity and reversible adsorptivity, from current-time traces recorded in a mesoscopic regime of very small amounts of analyte molecules. Electrochemiluminescence is the electrochemically triggered generation of light, it is using for sensitive biosensing. Using new transparent nanochannel devices, electrochemiluminescence is generated in nanoscale confinement, enabling efficient reaction pathways and intense light emission. Klaus Mathwig studied Nanostructuring Technology at the University of Würzburg (Germany) and obtained his PhD in Physics from the Max Planck Institute of Microstructure Physics (Germany) in 2010. Afterwards, he was a Postdoctoral Associate at ETH Zürich (Switzerland), and in the Nanoionics group at the MESA+ Institute for Nanotechnology, University of Twente (Netherlands). Since 2014 he has been Assistant Professor for Analytical Chemistry at the Groningen Research Institute of Pharmacy, University of Groningen (Netherlands). His research focuses on nanoscale electrochemistry and electrochemiluminescence.
Event Location: 
McMaster
Location Details: 
TBA